BDBM50206106 (8S,11R,13S,14R)-11-(4-dimethylamino-phenyl)-17-(4-fluoro-phenylethynyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one::(8S,11R,13S,14R,17S)-11-(4-Dimethylamino-phenyl)-17-(4-fluoro-phenylethynyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one::CHEMBL232219

SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(F)cc2)[C@@H]2OCC3=CC(=O)CCC3=C12

InChI Key InChIKey=QMITVKPWYUNGDV-ZDRBTZMISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206106   

TargetProgesterone receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50206106((8S,11R,13S,14R)-11-(4-dimethylamino-phenyl)-17-(4...)
Affinity DataIC50:  0.270nMAssay Description:Antagonist activity at human progesterone receptor assessed as inhibition of alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed